Stuart Scott, one of the most recognizable anchors in Sportscenter history, died of cancer at the age of 49, according to an ESPN press release.  “ESPN and everyone in the sports world have lost a true friend and a uniquely inspirational figure in Stuart Scott,” said ESPN president John Skipper in the statement.

Scott, who had two daughters, was known for his boisterous, high-energy delivery and catchphrases like “cool as the other side of the pillow.” He had been public about his long fight with the disease which he was diagnosed with in 2007. He remained highly active throughout his treatment, using mixed martial arts training to counteract the effects of chemotherapy.